He was a world authority on cosmic radiation study and he was proposed for the Nobel Prize in 1958. Blas Cabrera disciple, together they formulated the so-called Cabrera-Duperier law. After Spanish Civil War, he was exiled to England, where he worked as professor at University of Birmingham and at Imperial College London. He returns definitively to Spain in 1953 and begins to teach at his Chair at University of Madrid, taking advantage of a program started by Joaquín Ruiz-Giménez (National Education Minister) to bring back again exiled brains. But once he was back, he was not allowed to bring in to Spain the laboratory donated by British physicists. Duperier, who excelled at experimenting, could not continue his cosmic rays empirical investigation and was relegated to theoretical courses teaching.